The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells

The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells

In Parkinson’s disease (PD), gut inflammation is hypothesised to contribute to α-synuclein aggregation, but gastrointestinal α-synuclein expression is poorly characterised. Cationic arginine-rich peptides (CARPs) are an emerging therapeutic option that exerts various neuroprotective effects and may...

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Bibliographic Details
Main Authors:	Anastazja M. Gorecki, Holly Spencer, Bruno P. Meloni, Ryan S. Anderton
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Biomedicines
Subjects:	α-synuclein arginine poly-arginine R18D enteroendocrine cells pre-formed fibrils
Online Access:	https://www.mdpi.com/2227-9059/11/8/2089

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