The 5′ Untranslated Region of the <italic toggle="yes">EFG1</italic> Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in <italic toggle="yes">Candida albicans</italic>

The 5′ Untranslated Region of the <italic toggle="yes">EFG1</italic> Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in <italic toggle="yes">Candida albicans</italic>

ABSTRACT Extensive 5′ untranslated regions (UTR) are a hallmark of transcripts determining hyphal morphogenesis in Candida albicans. The major transcripts of the EFG1 gene, which are responsible for cellular morphogenesis and metabolism, contain a 5′ UTR of up to 1,170 nucleotides (nt). Deletion ana...

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Bibliographic Details
Main Authors: Prashant R. Desai, Klaus Lengeler, Mario Kapitan, Silas Matthias Janßen, Paula Alepuz, Ilse D. Jacobsen, Joachim F. Ernst
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
5′ UTR
Candida albicans
EFG1
filamentation
hyphal morphogenesis
posttranscriptional regulation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00280-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00280-18

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