Escherichia coli adhesion portion FimH polarizes M2 macrophages to M1 macrophages in tumor microenvironment via toll-like receptor 4

Escherichia coli adhesion portion FimH polarizes M2 macrophages to M1 macrophages in tumor microenvironment via toll-like receptor 4

BackgroundMacrophages are key effector cells of innate immunity and play a critical role in the immune balance of disease pathogenesis, especially in the tumor microenvironment. In previous studies, we showed that FimH, an Escherichia coli adhesion portion, promoted dendritic cell activation. Howeve...

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Bibliographic Details
Main Authors: Wei Zhang, Li Xu, Xiaoyan Zhang, Jianqing Xu, Jun-O Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
fimH
macrophage polarization
toll-like receptor 4
myeloid differentiation factor 2
tumor-associated macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213467/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213467/full

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