Allosteric Antagonism of the A<sub>2A</sub> Adenosine Receptor by a Series of Bitopic Ligands

Allosteric antagonism by bitopic ligands, as reported for many receptors, is a distinct modulatory mechanism. Although several bitopic A<sub>2A</sub> adenosine receptor (A<sub>2A</sub>AR) ligand classes were reported as pharmacological tools, their receptor binding and functi...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Zhan-Guo Gao, Kiran S. Toti, Ryan Campbell, R. Rama Suresh, Huijun Yang, Kenneth A. Jacobson
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: MDPI AG 2020-05-01
Sraith:Cells
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2073-4409/9/5/1200