Single-molecule FRET reveals proofreading complexes in the large fragment of <em>Bacillus stearothermophilus</em> DNA polymerase I

There is increasing interest in the use of DNA polymerases (DNA pols) in next-generation sequencing strategies. These methodologies typically rely on members of the A and B family of DNA polymerases that are classified as high-fidelity DNA polymerases. These enzymes possess the ability to selectivel...

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Bibliographic Details
Main Authors: Thomas V. Christian, William H. Konigsberg
Format: Article
Language:English
Published: AIMS Press 2018-05-01
Series:AIMS Biophysics
Subjects:
Online Access:http://www.aimspress.com/biophysics/article/2010/fulltext.html