Regulated expression of apolipoprotein E by human retinal pigment epithelial cells

Regulated expression of apolipoprotein E by human retinal pigment epithelial cells

In early age-related macular degeneration (AMD), lipid-containing deposits (drusen) accumulate in Bruch's membrane underlying the retinal pigment epithelium (RPE). Recent studies indicate that apolipoprotein E (apoE) may play a role in lipid trafficking in AMD. Compared with the apoE3 allele, t...

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Bibliographic Details
Main Authors: Brian Y. Ishida, Kathy R. Bailey, Keith G. Duncan, Robert J. Chalkley, A.L. Burlingame, John P. Kane, Daniel M. Schwartz
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Journal of Lipid Research
Subjects:
age-related macular degeneration
Bruch's membrane
retina
high density lipoprotein
thyroid hormone
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318976

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http://www.sciencedirect.com/science/article/pii/S0022227520318976

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