Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs

Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs

The most common primary central nervous system tumor in adults is the glioblastoma multiforme (GBM). The highly invasive nature of GBM cells is a significant factor resulting in the inevitable tumor recurrence and poor patient prognosis. Tumor cells utilize structures known as invadopodia to facilia...

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Bibliographic Details
Main Authors: Clarissa A. Whitehead, Hong P.T. Nguyen, Andrew P. Morokoff, Rodney B. Luwor, Lucia Paradiso, Andrew H. Kaye, Theo Mantamadiotis, Stanley S. Stylli
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318303371

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http://www.sciencedirect.com/science/article/pii/S1936523318303371

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