Changes in Cortisol but Not in Brain-Derived Neurotrophic Factor Modulate the Association Between Sleep Disturbances and Major Depression

Changes in Cortisol but Not in Brain-Derived Neurotrophic Factor Modulate the Association Between Sleep Disturbances and Major Depression

Sleep disturbance is a symptom consistently found in major depression and is associated with a longer course of illness, reduced response to treatment, increased risk of relapse and recurrence. Chronic insomnia has been associated with changes in cortisol and serum brain-derived neurotrophic factor...

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Bibliographic Details
Main Authors: Giuliana Travassos Pires Santiago, Ana Cecília de Menezes Galvão, Raíssa Nóbrega de Almeida, Sergio Arthuro Mota-Rolim, Fernanda Palhano-Fontes, João Paulo Maia-de-Oliveira, Dráulio Barros de Araújo, Bruno Lobão-Soares, Nicole Leite Galvão-Coelho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
pittsburgh sleep quality index
brain-derived neurotrophic factor
salivary cortisol awakening response
sleep disturbance
treatment-resistant depression
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2020.00044/full

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https://www.frontiersin.org/article/10.3389/fnbeh.2020.00044/full

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