Acute myeloid leukemia cells and MSC-derived exosomes inhibiting transformation in myelodysplastic syndrome

Acute myeloid leukemia cells and MSC-derived exosomes inhibiting transformation in myelodysplastic syndrome

Abstract Aims To investigate the mechanism of exosomes' role in the transformation of MDS to AML. Methods Exosomes in culture supernatants of MDS and AML cell lines, were extracted by ultrafiltration and identified in three ways: morphology, size, and exosome protein surface markers. Exosomes f...

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Bibliographic Details
Main Authors: Xiaoli Liu, Fanggang Ren, Shuo Li, Na Zhang, Jeffrey J. Pu, Hongyu Zhang, Zhifang Xu, Yanhong Tan, Xiuhua Chen, Jianmei Chang, Hongwei Wang
Format: Article
Language:English
Published: Springer 2023-06-01
Series:Discover Oncology
Subjects:
MDS
AML
Mesenchymal stem cells
Transformation
Exosomes
Online Access:https://doi.org/10.1007/s12672-023-00714-2

Internet

https://doi.org/10.1007/s12672-023-00714-2

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