Overexpression of angiogenic factors and matrix metalloproteinases in the saliva of oral squamous cell carcinoma patients: potential non-invasive diagnostic and therapeutic biomarkers

Overexpression of angiogenic factors and matrix metalloproteinases in the saliva of oral squamous cell carcinoma patients: potential non-invasive diagnostic and therapeutic biomarkers

Abstract Backgrounds Salivary biomarkers hold huge potential for the non-invasive diagnosis of oral squamous cell carcinoma. Angiogenic factors and matrix-metalloproteinases (MMPs) are highly expressed in OSCC tissue, but their expression patterns in the saliva are unknown. This study aimed to analy...

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Bibliographic Details
Main Authors: Meijuan Cai, Zhichao Zheng, Zhibao Bai, Kexiong Ouyang, Qiuyu Wu, Shaofen Xu, Lihuan Huang, Yingtong Jiang, Lijing Wang, Jie Gao, Janak L. Pathak, Lihong Wu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Angiogenic factors
Diagnostic markers
MMPs
Oral squamous cell carcinoma
Saliva
Online Access:https://doi.org/10.1186/s12885-022-09630-0

Internet

https://doi.org/10.1186/s12885-022-09630-0

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