Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals
We recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wech...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-01-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/13/2/284 |
| _version_ | 1797409151554420736 |
|---|---|
| author | Keisuke Sakurai Chutong Shen Izumi Shiraishi Noriko Inamura Tatsuhiro Hisatsune |
| author_facet | Keisuke Sakurai Chutong Shen Izumi Shiraishi Noriko Inamura Tatsuhiro Hisatsune |
| author_sort | Keisuke Sakurai |
| collection | DOAJ |
| description | We recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wechsler Memory Scale-Delayed Recall (WMS-DR), and daily nutrient intake was estimated from a Brief-type Self-administered Diet History Questionnaire (BDHQ). By a multiple regression analysis, among the four major nutrients (protein, fat, carbohydrate and ash), we detected a significant correlation between the score of cognitive functions assessed by both MoCA and WMS-DR and daily consumption of fat (<i>p</i> = 0.0317 and <i>p</i> = 0.0111, respectively). Among categories of fatty acid, we found a significant correlation between the score of both MoCA and WMS-DR and consumption of monounsaturated fatty acid (MUFA) (<i>p</i> = 0.0157 and <i>p</i> = 0.0136, respectively). Finally, among MUFAs, we observed a significant correlation between the score of both MoCA and WMS-DR and consumption of oleic acid (<i>p</i> = 0.0405 and <i>p</i> = 0.0165, respectively). From these observations, we can propose that daily consumption of fat, especially in oleic acid, has a beneficial effect against cognitive decline in community-dwelling Japanese elderly individuals. |
| first_indexed | 2024-03-09T04:09:13Z |
| format | Article |
| id | doaj.art-f135f405caa546b3ac2faaf4d37170c2 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T04:09:13Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f135f405caa546b3ac2faaf4d37170c22023-12-03T14:02:35ZengMDPI AGNutrients2072-66432021-01-0113228410.3390/nu13020284Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly IndividualsKeisuke Sakurai0Chutong Shen1Izumi Shiraishi2Noriko Inamura3Tatsuhiro Hisatsune4Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, JapanDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, JapanDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, JapanCommunity Health Promotion Laboratory, Mitsui Fudosan, Co., Ltd., Kashiwa 277-8519, JapanDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, JapanWe recruited 154 community-dwelling elderly individuals and conducted a cohort study to find out the nutrient intake that is suitable for maintaining cognitive function in Japanese elders. Cognitive function was evaluated by the two functional tests, the Montreal Cognitive Assessment (MoCA) and Wechsler Memory Scale-Delayed Recall (WMS-DR), and daily nutrient intake was estimated from a Brief-type Self-administered Diet History Questionnaire (BDHQ). By a multiple regression analysis, among the four major nutrients (protein, fat, carbohydrate and ash), we detected a significant correlation between the score of cognitive functions assessed by both MoCA and WMS-DR and daily consumption of fat (<i>p</i> = 0.0317 and <i>p</i> = 0.0111, respectively). Among categories of fatty acid, we found a significant correlation between the score of both MoCA and WMS-DR and consumption of monounsaturated fatty acid (MUFA) (<i>p</i> = 0.0157 and <i>p</i> = 0.0136, respectively). Finally, among MUFAs, we observed a significant correlation between the score of both MoCA and WMS-DR and consumption of oleic acid (<i>p</i> = 0.0405 and <i>p</i> = 0.0165, respectively). From these observations, we can propose that daily consumption of fat, especially in oleic acid, has a beneficial effect against cognitive decline in community-dwelling Japanese elderly individuals.https://www.mdpi.com/2072-6643/13/2/284cognitive functionmemory functionagingfatMUFAoleic acid |
| spellingShingle | Keisuke Sakurai Chutong Shen Izumi Shiraishi Noriko Inamura Tatsuhiro Hisatsune Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals Nutrients cognitive function memory function aging fat MUFA oleic acid |
| title | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
| title_full | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
| title_fullStr | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
| title_full_unstemmed | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
| title_short | Consumption of Oleic Acid on the Preservation of Cognitive Functions in Japanese Elderly Individuals |
| title_sort | consumption of oleic acid on the preservation of cognitive functions in japanese elderly individuals |
| topic | cognitive function memory function aging fat MUFA oleic acid |
| url | https://www.mdpi.com/2072-6643/13/2/284 |
| work_keys_str_mv | AT keisukesakurai consumptionofoleicacidonthepreservationofcognitivefunctionsinjapaneseelderlyindividuals AT chutongshen consumptionofoleicacidonthepreservationofcognitivefunctionsinjapaneseelderlyindividuals AT izumishiraishi consumptionofoleicacidonthepreservationofcognitivefunctionsinjapaneseelderlyindividuals AT norikoinamura consumptionofoleicacidonthepreservationofcognitivefunctionsinjapaneseelderlyindividuals AT tatsuhirohisatsune consumptionofoleicacidonthepreservationofcognitivefunctionsinjapaneseelderlyindividuals |