FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway

FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway

F-box/WD repeat-containing protein 5 (FBXW5) is a member of the FBXW subclass of F-box proteins. Despite its known function as a component of the Skp1-Cullin-F-box (SCF) ubiquitin ligase complex, the role of FBXW5 in gastric cancer tumorigenesis and metastasis has not been investigated. The present...

Full description

Bibliographic Details
Main Authors: Mei Shi Yeo, Vinod Vijay Subhash, Kazuto Suda, Hayri Emrah Balcıoğlu, Siqin Zhou, Win Lwin Thuya, Xin Yi Loh, Sriganesh Jammula, Praveen C. Peethala, Shi Hui Tan, Chen Xie, Foong Ying Wong, Benoit Ladoux, Yoshiaki Ito, Henry Yang, Boon Cher Goh, Lingzhi Wang, Wei Peng Yong
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
FBXW5 (F-box/WD repeat-containing protein 5), tumorigenesis
metastasis
FAK-Src signaling
Online Access:https://www.mdpi.com/2072-6694/11/6/836

Internet

https://www.mdpi.com/2072-6694/11/6/836

Similar Items