Acinar cell apoptosis in Serpini2-deficient mice models pancreatic insufficiency.
Pancreatic insufficiency (PI) when left untreated results in a state of malnutrition due to an inability to absorb nutrients. Frequently, PI is diagnosed as part of a larger clinical presentation in cystic fibrosis or Shwachman-Diamond syndrome. In this study, a mouse model for isolated exocrine PI...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2005-09-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1231717?pdf=render |