Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion

Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion

Herein, we report the synthesis, antioxidant, and neuroprotective properties of some nucleobase-derived nitrones named <b>9a</b>–<b>i</b>. The neuroprotective properties of nitrones, <b>9a</b>–<b>i</b>, were measured against an oxygen-glucose-deprivati...

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Bibliographic Details
Main Authors: Beatriz Chamorro, Iwona E. Głowacka, Joanna Gotkowska, Rafał Gulej, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, Dorota G. Piotrowska, María Jesús Oset-Gasque
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
antioxidants
neuroprotection
necrosis
apoptosis
oxidative stress
nucleobase-derived nitrones
Online Access:https://www.mdpi.com/1422-0067/23/6/3411

Internet

https://www.mdpi.com/1422-0067/23/6/3411

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