Increased meso-striatal connectivity mediates trait impulsivity in FTO variant carriers

ObjectiveWhile variations in the first intron of the fat mass and obesity-associated gene (FTO, rs9939609 T/A variant) have long been identified as a major contributor to polygenic obesity, the mechanisms underlying weight gain in risk allele carriers still remain elusive. On a behavioral level, FTO...

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Bibliographic Details
Main Authors: Sharmili Edwin Thanarajah, Ruth Hanssen, Corina Melzer, Marc Tittgemeyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1130203/full