Plasma CXCL4–DNA/RNA Complexes and Anti-CXCL4 Antibodies Modulation in an SSc Cohort under Iloprost Treatment

Plasma CXCL4–DNA/RNA Complexes and Anti-CXCL4 Antibodies Modulation in an SSc Cohort under Iloprost Treatment

Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular and immunity alterations and skin/internal organ fibrosis. Aberrant levels of plasma CXCL4, CXCL4–RNA/DNA complexes, type I IFN (IFN-I) and anti-CXCL4 antibodies characterize SSc. These parameters influence each...

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Bibliographic Details
Main Authors: Anna Mennella, Katia Stefanantoni, Raffaella Palazzo, Giuseppe Ocone, Immacolata Pietraforte, Simona Truglia, Ilaria Bisconti, Alba Pisacreta, Valeria Riccieri, Roberto Lande, Loredana Frasca
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Reports
Subjects:
systemic sclerosis (SSc)
iloprost
type I interferon (IFN-I)
CXCL4
plasmacytoid dendritic cells (pDCs)
Online Access:https://www.mdpi.com/2571-841X/7/3/66

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https://www.mdpi.com/2571-841X/7/3/66

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