Inactivation of the Mla system and outer-membrane phospholipase A results in disrupted outer-membrane lipid asymmetry and hypervesiculation in Bordetella pertussis

Bordetella pertussis is the causative agent of a respiratory infection known as whooping cough. With the goal of improving the production of outer-membrane vesicles (OMVs), we studied here the mechanisms that are involved in maintaining lipid asymmetry in the outer membrane of this organism. We iden...

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Bibliographic Details
Main Authors: Eline F. de Jonge, Lana Vogrinec, Ria van Boxtel, Jan Tommassen
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Microbial Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517422000694