The Organization and Function of the Phagophore-ER Membrane Contact Sites

Macroautophagy is characterized by the de novo formation of double-membrane vesicles termed autophagosomes. The precursor structure of autophagosomes is a membrane cistern called phagophore, which elongates through a massive acquisition of lipids until closure. The phagophore establishes membrane-co...

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Bibliographic Details
Main Authors: Prado Vargas Duarte, Fulvio Reggiori
Format: Article
Language:English
Published: SAGE Publishing 2023-07-01
Series:Contact
Online Access:https://doi.org/10.1177/25152564231183898