Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease

Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is associated with hepatic as well as systemic insulin resistance even in the absence of type 2 diabetes. The extent and pathways through which hepatic inflammation modulates insulin sensitivity in NAFLD are only partially understood. We e...

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Bibliographic Details
Main Authors: Nadine Gehrke, Lea J. Hofmann, Beate K. Straub, Frank Rühle, Ari Waisman, Peter R. Galle, Jörn M. Schattenberg
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Clinical and Translational Medicine
Subjects:
cirrhosis
hepatic steatosis
obesity
type 2 diabetes
Online Access:https://doi.org/10.1002/ctm2.1048

Internet

https://doi.org/10.1002/ctm2.1048

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