Bone health in autosomal dominant polycystic kidney disease (ADPKD) patients after kidney transplantation

Bone health in autosomal dominant polycystic kidney disease (ADPKD) patients after kidney transplantation

ADPKD is caused by pathogenic variants in PKD1 or PKD2, encoding polycystin-1 and -2 proteins. Polycystins are expressed in osteoblasts and chondrocytes in animal models, and loss of function is associated with low bone mineral density (BMD) and volume. However, it is unclear whether these variants...

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Bibliographic Details
Main Authors: Dalia Zubidat, Christian Hanna, Amarjyot K. Randhawa, Byron H. Smith, Maroun Chedid, Daniel-Hasan N. Kaidbay, Luca Nardelli, Yaman G. Mkhaimer, Reem M. Neal, Charles D. Madsen, Sarah R. Senum, Adriana V. Gregory, Timothy L. Kline, Ziad M. Zoghby, Stephen M. Broski, Naim S. Issa, Peter C. Harris, Vicente E. Torres, Jad G. Sfeir, Fouad T. Chebib
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
ADPKD
Transplantation
Bone
Mineral metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000037

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http://www.sciencedirect.com/science/article/pii/S2352187223000037

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