Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism.

Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism.

Most forms of chronic kidney disease are characterized by progressive renal and cardiac fibrosis leading to dysfunction. Preliminary evidence suggests that various bone marrow-derived cell populations have antifibrotic effects. In exploring the therapeutic potential of bone marrow derived cells in c...

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Bibliographic Details
Main Authors: Darren A Yuen, Kim A Connelly, Andrew Advani, Christine Liao, Michael A Kuliszewski, Judy Trogadis, Kerri Thai, Suzanne L Advani, Yuan Zhang, Darren J Kelly, Howard Leong-Poi, Armand Keating, Philip A Marsden, Duncan J Stewart, Richard E Gilbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2832011?pdf=render

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http://europepmc.org/articles/PMC2832011?pdf=render

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