The expanding Pandora’s toolbox of CD8+T cell: from transcriptional control to metabolic firing

Abstract CD8+ T cells are the executor in adaptive immune response, especially in anti-tumor immunity. They are the subset immune cells that are of high plasticity and multifunction. Their development, differentiation, activation and metabolism are delicately regulated by multiple factors. Stimuli f...

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Bibliographic Details
Main Authors: Jinghong Wu, Zhendong Lu, Hong Zhao, Mingjun Lu, Qing Gao, Nanying Che, Jinghui Wang, Teng Ma
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04775-3