A proteomic view at T cell costimulation.
The "two-signal paradigm" in T cell activation predicts that the cooperation of "signal 1," provided by the T cell receptor (TCR) through engagement of major histocompatility complex (MHC)-presented peptide, with "signal 2″ provided by costimulatory molecules, the prototype...
| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Public Library of Science (PLoS)
2012-01-01
|
| Серии: | PLoS ONE |
| Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22539942/?tool=EBI |