Protective Effect of Metformin on Gentamicin-Induced Vestibulotoxicity in Rat Primary Cell Culture

ObjectivesOne of the antidiabetic drugs, metformin, have shown that it prevented oxidative stress-induced death in several cell types through a mechanism involving the opening of the permeability transition pore and cytochrome c release. Thus, it is possible that the antioxidative effect of metformi...

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Bibliographic Details
Main Authors: Ji Young Lee, Se Hee Lee, Ji Won Chang, Jae-June Song, Hak Hyun Jung, Gi Jung Im
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2014-12-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Online Access:http://www.e-ceo.org/upload/pdf/ceo-7-286.pdf