Hepatic pannexin‐1 mediates ST2+ regulatory T cells promoting resolution of inflammation in lipopolysaccharide‐induced endotoxemia

Hepatic pannexin‐1 mediates ST2+ regulatory T cells promoting resolution of inflammation in lipopolysaccharide‐induced endotoxemia

Abstract Sepsis remains the most lethal infectious disease and substantially impairs patient prognosis after liver transplantation (LT). Our previous study reported a role of the pannexin 1 (PANX1)–interleukin‐33 (IL‐33) axis in activating innate immunity to protect against methicillin‐resistant Sta...

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Bibliographic Details
Main Authors: Pusen Wang, Baojie Shi, Chunguang Wang, Yuanyuan Wang, Weitao Que, Zhongyi Jiang, Xueni Liu, Qianwei Jiang, Hao Li, Zhihai Peng, Lin Zhong
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Clinical and Translational Medicine
Subjects:
ATP
endotoxemia
IL‐33
Panx1
Tregs
Online Access:https://doi.org/10.1002/ctm2.849

Internet

https://doi.org/10.1002/ctm2.849

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