Germline BRCA1 and BRCA2 mutations and the risk of bladder or kidney cancer in Poland

Germline BRCA1 and BRCA2 mutations and the risk of bladder or kidney cancer in Poland

Abstract Introduction The role of the BRCA1 and BRCA2 genes in bladder and renal tumorigenesis is unclear. Our goal was to determine the prevalence of specific founder mutations genes BRCA1 (5328 insC, C61G and 4153 delA) and BRCA2 (C5972T) mutations in bladder and kidney cancer patients from Poland...

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Bibliographic Details
Main Authors: Elżbieta Złowocka-Perłowska, Aleksandra Tołoczko-Grabarek, Steven A. Narod, Jan Lubiński
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Mutation: 5328 insC
C61G
4153 delA
C5972T; gene: BRCA1
BRCA2
Online Access:https://doi.org/10.1186/s13053-022-00220-6

Internet

https://doi.org/10.1186/s13053-022-00220-6

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