Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration

Abstract Background Age-related macular degeneration (AMD) is the leading cause of blindness in elderly people in the developed world, and the number of people affected is expected to almost double by 2040. The retina presents one of the highest metabolic demands in our bodies that is partially or f...

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Bibliographic Details
Main Authors: Juan Ignacio Jiménez-Loygorri, Álvaro Viedma-Poyatos, Raquel Gómez-Sintes, Patricia Boya
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-024-00739-3