Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4

Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4

Patients with triple-negative breast cancer (TNBC) have a poor prognosis, partly because of the absence of targeted therapies. Recognition of the key role of immune responses against cancer has allowed the advent of immunotherapy, focused on the inhibition of negative immune checkpoints, such as CTL...

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Main Authors: María G. C. Navarrete-Bernal, Mayte G. Cervantes-Badillo, Jose Fabián Martínez-Herrera, César O. Lara-Torres, Raquel Gerson-Cwilich, Alejandro Zentella-Dehesa, María de Jesús Ibarra-Sánchez, José Esparza-López, Juan J. Montesinos, Víctor Adrián Cortés-Morales, Diego Osorio-Pérez, Diana A. Villegas-Osorno, Eduardo Reyes-Sánchez, Pablo Salazar-Sojo, Luis F. Tallabs-Utrilla, Sandra Romero-Córdoba, Leticia Rocha-Zavaleta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer
CTLA-4
immunotherapy
immune landscape
cancer genomics
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01206/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01206/full

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