Proteomic analysis of aorta and protective effects of grape seed procyanidin B2 in db/db mice reveal a critical role of milk fat globule epidermal growth factor-8 in diabetic arterial damage.

Proteomic analysis of aorta and protective effects of grape seed procyanidin B2 in db/db mice reveal a critical role of milk fat globule epidermal growth factor-8 in diabetic arterial damage.

BACKGROUND: Atherosclerosis is one of the major complications of type 2 diabetic patients (T2DM), leading to morbidity and mortality. Grape seed procyanidin B2 (GSPB2) has demonstrated protective effect against atherosclerosis, which is believed to be, at least in part, a result of its antioxidative...

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Bibliographic Details
Main Authors: Fei Yu, Bao-ying Li, Xiao-li Li, Qian Cai, Zhen Zhang, Mei Cheng, Mei Yin, Jun-fu Wang, Jian-hua Zhang, Wei-da Lu, Rui-hai Zhou, Hai-qing Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528673?pdf=render

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http://europepmc.org/articles/PMC3528673?pdf=render

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