Whole-exome sequencing reveals genomic landscape of intrahepatic cholangiocarcinoma and identifies SAV1 as a potential driver

Abstract Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma, with poor prognosis and limited treatment options. The genomic features of ICC in Chinese patients remain largely unknown. In this study, we perform deep whole-exome se...

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Bibliographic Details
Main Authors: Zheng-Jun Zhou, Yu-Hang Ye, Zhi-Qiang Hu, Yue-Ru Hou, Kai-Xuan Liu, Rong-Qi Sun, Peng-Cheng Wang, Chu-Bin Luo, Jia Li, Ji-Xue Zou, Jian Zhou, Jia Fan, Cheng-Li Song, Shao-Lai Zhou
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54387-8