The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.

Eukaryotic mRNA decay is a highly regulated process allowing cells to rapidly modulate protein production in response to internal and environmental cues. Mature translatable eukaryotic mRNAs are protected from fast and uncontrolled degradation in the cytoplasm by two cis-acting stability determinant...

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Bibliographic Details
Main Authors: Zaineb Fourati, Olga Kolesnikova, Régis Back, Jenny Keller, Clément Charenton, Valerio Taverniti, Claudine Gaudon Plesse, Noureddine Lazar, Dominique Durand, Herman van Tilbeurgh, Bertrand Séraphin, Marc Graille
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4022514?pdf=render