The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma

The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma

Fat mass and obesity-associated (FTO) protein, the first m6A demethylase identified in 2011, regulates multiple aspects of RNA biology including splicing, localization, stability, and translation. Accumulating data show that FTO is involved in numerous physiological processes and is implicated in mu...

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Bibliographic Details
Main Authors: Dalin Zhang, Sarah Wornow, Donna M. Peehl, Erinn B. Rankin, James D. Brooks
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Translational Oncology
Subjects:
m6A RNA demethylase
FTO
Renal cell carcinoma
Cancer progression
Prognosis
Inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322001772

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http://www.sciencedirect.com/science/article/pii/S1936523322001772

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