Pre-marketing immunogenicity and safety of a lyophilized purified human diploid cell rabies vaccine produced from microcarrier cultures: a randomized clinical trial

The large-scale production of a human diploid cell (HDC) vaccine (HDCV) for rabies is limited by several technical challenges. Kanghua Biological Products Co., Ltd., has successfully used microcarrier technology for the large-scale culture of HDCs in bioreactors to develop a lyophilized and purified...

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Bibliographic Details
Main Authors: Xingyu Zhou, Xiaohong Wu, Yong Cai, Shouchun Cao, Xiaoping Zhu, Qiang Lv, Huaigong Chen, Leitai Shi, Jia Li, Xinjie Wang, Yuhua Li, Rong Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2018.1549450