A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks

The mechanism of axon growth and guidance is a core, unsolved problem in neuroscience and cell biology. For nearly three decades, our view of this process has largely been based on deterministic models of motility derived from studies of neurons cultured in vitro on rigid substrates. Here, we sugges...

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Bibliographic Details
Main Authors: Rameen Forghani, Aravind Chandrasekaran, Garegin Papoian, Edward Giniger
Format: Article
Language:English
Published: The Royal Society 2023-06-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220359