Evaluation of HLA typing content of next-generation sequencing datasets from family trios and individuals of arab ethnicity

Evaluation of HLA typing content of next-generation sequencing datasets from family trios and individuals of arab ethnicity

Introduction: HLA typing is a critical tool in both clinical and research applications at the individual and population levels. Benchmarking studies have indicated HLA-HD as the preferred tool for accurate and comprehensive HLA allele calling. The advent of next-generation sequencing (NGS) has revol...

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Bibliographic Details
Main Authors: Mohammed Dashti, Md Zubbair Malik, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Genetics
Subjects:
HLA typing
consistency
resolutions
reproducibility
next-generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1407285/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2024.1407285/full

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