The Protective Role of pVHL in Imiquimod-Induced Psoriasis-like Skin Inflammation

The Protective Role of pVHL in Imiquimod-Induced Psoriasis-like Skin Inflammation

Psoriasis is a chronic inflammatory disease distinguished by an excessive proliferation and abnormal differentiation of keratinocytes. Immune cells, such as T lymphocytes and neutrophils, and inflammatory cytokines, such as Tumor Necrosis Factor-α (TNF-α) and interleukin 17 (IL-17), are essential fo...

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Bibliographic Details
Main Authors: Isaí Martínez-Torres, Araceli Tepale-Segura, Octavio Castro-Escamilla, Juan Carlos Cancino-Diaz, Sandra Rodríguez-Martínez, Sonia Mayra Perez-Tapia, Laura C. Bonifaz, Mario Eugenio Cancino-Diaz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
psoriasis
von Hippel-Lindau protein (pVHL)
hypoxia-inducible factor-1α (HIF-1α)
angiogenesis
neutrophils
IL-17
Online Access:https://www.mdpi.com/1422-0067/23/9/5226

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https://www.mdpi.com/1422-0067/23/9/5226

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