Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children

Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children

Integrase inhibitors (INIs) are a potent option for HIV treatment. Limited data exist on INI resistance in West Africa, particularly in children living with HIV/AIDS. We determined the prevalence of integrase gene polymorphisms and the frequency of naturally occurring amino acid (aa) substitutions a...

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Bibliographic Details
Main Authors: Djeneba B. Fofana, Houdou Diarra, Ibrahima Guindo, Mahamadou K. Savadogo, Marceline d’Almeida, Fatoumata I. Diallo, Aliou Baldé, Cathia Soulié, Amadou Kone, Anne-Geneviève Marcelin, Almoustapha I. Maiga, Sidonie Lambert-Niclot, Mamoudou Maiga, Sally McFall, Claudia A. Hawkins, Robert L. Murphy, Mariam Sylla, Christine Katlama, Jane L. Holl, Vincent Calvez, Laurence Morand-Joubert
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
HIV-1
polymorphism
integrase
children
resistance
Africa
Online Access:https://www.mdpi.com/1999-4915/15/2/546

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https://www.mdpi.com/1999-4915/15/2/546

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