Biotechnological production optimization of argyrins – a potent immunomodulatory natural product class
Summary Argyrins represent a family of cyclic octapeptides exhibiting promising immunomodulatory activity via inhibiting mitochondrial protein synthesis, which leads to reduced IL‐17 production by the T‐helper 17 cells. Argyrins are formed by a non‐ribosomal peptide synthetase (NRPS), originating fr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Microbial Biotechnology |
| Online Access: | https://doi.org/10.1111/1751-7915.13959 |