Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity
Abstract Although the exact pathogenesis of idiopathic pulmonary fibrosis (IPF) is still unknown, the transdifferentiation of fibroblasts into myofibroblasts and the production of extracellular matrix components such as collagen, triggered by alveolar epithelial cell injury, are important mechanisms...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-02-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-00851-7 |