Polymorphism of alcohol metabolizing gene ADH3 predisposes to development of alcoholic pancreatitis in North Indian population

Polymorphism of alcohol metabolizing gene ADH3 predisposes to development of alcoholic pancreatitis in North Indian population

Background and aim- Genetic factors regulating alcohol metabolism could predispose in developing alcoholic pancreatitis (ACP). Studies revealed that alcohol could be metabolized by both ways, oxidative and non-oxidative. The main oxidative pathway includes alcohol dehydrogenase (ADH), aldehyde dehyd...

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Bibliographic Details
Main Authors: Divya eSingh, Tajwar Singh Negi, Ghanshyam eUpadhyay, Gourdas eChoudhuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alcohol Dehydrogenase
Polymorphism, Single Nucleotide
Chronic pancreatitis
CYP2E1
ADH3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00067/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00067/full

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