Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23

Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23

Abstract Osteocytes act within a hypoxic environment to control key steps in bone formation. FGF23, a critical phosphate-regulating hormone, is stimulated by low oxygen/iron in acute and chronic diseases, however the molecular mechanisms directing this process remain unclear. Our goal was to identif...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Megan L. Noonan, Pu Ni, Emmanuel Solis, Yamil G. Marambio, Rafiou Agoro, Xiaona Chu, Yue Wang, Hongyu Gao, Xiaoling Xuei, Erica L. Clinkenbeard, Guanglong Jiang, Sheng Liu, Steve Stegen, Geert Carmeliet, William R. Thompson, Yunlong Liu, Jun Wan, Kenneth E. White
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Nature Publishing Group 2023-01-01
Sarja:Bone Research
Linkit:https://doi.org/10.1038/s41413-022-00241-w

Internet

https://doi.org/10.1038/s41413-022-00241-w

Samankaltaisia teoksia