Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases

Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases

Summary: Microglia play an important role in neuroinflammation and neurodegeneration. Here, we report an approach for generating microglia-containing cerebral organoids derived from human pluripotent stem cells involving the supplementation of growth factors (FGF, EGF, heparin) and 10% CO2 culture c...

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Bibliographic Details
Main Authors: Yiling Hong, Xu Dong, Lawrence Chang, Chen Xie, Mariann Chang, Jose S. Aguilar, Jimmy Lin, Juncheng Lin, Qingshun Q. Li
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Neuroscience
Immunology
Cell biology
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003449

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http://www.sciencedirect.com/science/article/pii/S2589004223003449

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