Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice

Abstract Despite the established roles of the dopaminergic system in promoting arousal, the effects of loss of dopamine on the patterns of sleep and wakefulness remain elusive. Here, we examined the sleep architecture of dopamine-deficient (DD) mice, which were previously developed by global knockou...

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Bibliographic Details
Main Authors: Mitsuaki Kashiwagi, Mika Kanuka, Kaeko Tanaka, Masayo Fujita, Ayaka Nakai, Chika Tatsuzawa, Kazuto Kobayashi, Kazutaka Ikeda, Yu Hayashi
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00879-3