Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study.

The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumo...

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Bibliographic Details
Main Authors: Hirotoshi Sugino, Shigeru Tsumura, Masaru Kunimoto, Masuhiro Noda, Daisuke Chikuie, Chieko Noda, Mariko Yamashita, Hiroshi Watanabe, Hidemasa Ishii, Toru Tashiro, Kazuhiro Iwata, Takashi Kono, Kaoru Tsumura, Takahiro Sumiya, Sachio Takeno, Katsuhiro Hirakawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4562603?pdf=render