Transgenic fluorescent Plasmodium cynomolgi liver stages enable live imaging and purification of Malaria hypnozoite-forms.

Transgenic fluorescent Plasmodium cynomolgi liver stages enable live imaging and purification of Malaria hypnozoite-forms.

A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can cause renewed clinical disease after reactivation through unknown mechanisms. The closely related non-human primate malaria P. cynomolgi is a fr...

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Bibliographic Details
Main Authors: Annemarie Voorberg-van der Wel, Anne-Marie Zeeman, Sandra M van Amsterdam, Alexander van den Berg, Els J Klooster, Shiroh Iwanaga, Chris J Janse, Geert-Jan van Gemert, Robert Sauerwein, Niels Beenhakker, Gerrit Koopman, Alan W Thomas, Clemens H M Kocken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554669?pdf=render

Internet

http://europepmc.org/articles/PMC3554669?pdf=render

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