Clinical relevance of circulating ESR1 mutations during endocrine therapy for advanced hormone-dependent endometrial carcinoma

Clinical relevance of circulating ESR1 mutations during endocrine therapy for advanced hormone-dependent endometrial carcinoma

Abstract Objective Endocrine therapy is frequently administered in patients with hormone dependent (HR+) metastatic endometrial cancer. ESR1 mutations have emerged as a key mechanism of aromatase inhibitor (AI) resistance in HR + metastatic breast cancer and can be monitored using circulating tumor...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Aurélien Drouyer, Ludivine Beaussire, Pauline Jorda, Marianne Leheurteur, Cécile Guillemet, Anca Berghian, Dragos Georgescu, Frédéric Di Fiore, Anne Perdrix, Florian Clatot
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2023-11-01
Σειρά:BMC Cancer
Θέματα:
ESR1 mutation
Endometrial cancer
Circulating tumor DNA
Digital droplet PCR
Διαθέσιμο Online:https://doi.org/10.1186/s12885-023-11559-x

Διαδίκτυο

https://doi.org/10.1186/s12885-023-11559-x

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