Alu hypermethylation and high oxidative stress in patients with musculoskeletal tumors

Alu hypermethylation and high oxidative stress in patients with musculoskeletal tumors

Background Alu is one of the non-autonomous element retrotransposons, constituting nearly 11% of the human DNA. Methylation changes of the Alu element can cause genomic instability, a hallmark of cancer development, ultimately leading to the development of cancer. Epigenetic factors may induce the a...

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Bibliographic Details
Main Authors: Thamonwan Woraruthai, Chris Charoenlap, Chindanai Hongsaprabhas, Apiwat Mutirangura, Sittisak Honsawek
Format: Article
Language:English
Published: PeerJ Inc. 2018-08-01
Series:PeerJ
Subjects:
Alu methylation
8-OHdG
Blood leukocytes
Oxidative stress
Musculoskeletal tumors
Online Access:https://peerj.com/articles/5492.pdf

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https://peerj.com/articles/5492.pdf

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