Case report: Fractional brain tumor burden magnetic resonance mapping to assess response to pulsed low-dose-rate radiotherapy in newly-diagnosed glioblastoma

Case report: Fractional brain tumor burden magnetic resonance mapping to assess response to pulsed low-dose-rate radiotherapy in newly-diagnosed glioblastoma

BackgroundPulsed low-dose-rate radiotherapy (pLDR) is a commonly used reirradiation technique for recurrent glioma, but its upfront use with temozolomide (TMZ) following primary resection of glioblastoma is currently under investigation. Because standard magnetic resonance imaging (MRI) has limitati...

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Bibliographic Details
Main Authors: Ryan F. Amidon, Fernando Santos-Pinheiro, Michael Straza, Melissa A. Prah, Wade M. Mueller, Max O. Krucoff, Jennifer M. Connelly, Christopher J. Kleefisch, Dylan J. Coss, Elizabeth J. Cochran, Joseph A. Bovi, Christopher J. Schultz, Kathleen M. Schmainda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
pulsed low-dose-rate radiotherapy (pLDR)
MRI
fractional tumor burden (FTB)
relative cerebral blood volume (rCBV)
pseudoprogression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1066191/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1066191/full

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