The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B

The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B

Apoptosis-linked gene 2 (ALG-2, also known as PDCD6) is a member of the penta-EF-hand (PEF) family of Ca<sup>2+</sup>-binding proteins. The murine gene encoding ALG-2 was originally reported to be an essential gene for apoptosis. However, the role of ALG-2 in cell death pathways has rema...

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Bibliographic Details
Main Authors: Ryuta Inukai, Kanako Mori, Keiko Kuwata, Chihiro Suzuki, Masatoshi Maki, Terunao Takahara, Hideki Shibata
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
adaptor
calcium-binding protein
cell death
ESCRT-I
<i>PDCD6</i>
protein-protein interaction
Online Access:https://www.mdpi.com/1422-0067/22/3/1175

Internet

https://www.mdpi.com/1422-0067/22/3/1175

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