Hepatitis B Virus Protein X Induces Degradation of Talin-1

Hepatitis B Virus Protein X Induces Degradation of Talin-1

In the infected human hepatocyte, expression of the hepatitis B virus (HBV) accessory protein X (HBx) is essential to maintain viral replication in vivo. HBx critically interacts with the host damaged DNA binding protein 1 (DDB1) and the associated ubiquitin ligase machinery, suggesting that HBx fun...

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Bibliographic Details
Main Authors: Maarten A. A. van de Klundert, Maartje van den Biggelaar, Neeltje A. Kootstra, Hans L. Zaaijer
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Viruses
Subjects:
hepatitis B virus
protein X
TLN1
HBx
HBV
viral restriction
HBV transcription
Online Access:http://www.mdpi.com/1999-4915/8/10/281

Internet

http://www.mdpi.com/1999-4915/8/10/281

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